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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5655 | mAChR-IN-1 hydrochloride | AChR | |
mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 Nm. | |||
T5476 | mAChr-in-1 | AChR | |
mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM). | |||
T19870 | Aceclidine | 3-Acetoxyquinuclidine,1-azabicyclo[2.2.2]octan-3-yl acetate,NSC657843,3-quinuclidinyl acetate,NSC-657843,Glaucostat,NSC 657843,Quinuclidin-3-yl acetate | AChR |
Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular pressure. | |||
T14345 | Atropine methyl bromide | Methylatropine bromide | AChR |
Atropine methyl bromide (Methylatropine bromide) is a quaternary ammonium salt of atropine, characterized as a muscarinic receptor (mAChR) antagonist. It functions as a mydriatic to dilate the pupil during ophthalmic exa... | |||
T60536 | Terodiline | ||
Terodiline is a Ca 2+ blocker and M1-selective muscarinic receptor (mAChR) antagonist with Kb of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2), bladder (M3) and ileal muscle (M3), respectively. Terodil... | |||
T61878 | N-Demethyl MK-6884 | ||
N-Demethyl MK-6884 (compound 34) is an influential allosteric modulator of the M4 mAChR, which finds applicability in Alzheimer's disease research as well as the study of other diseases influenced by the M4 mAChR [1]. | |||
T60577 | Cycrimine | ||
Cycrimine is an orally active antagonist of the muscarinic cholinergic receptor (mAChR) M1 that reduces the level of acetylcholine in the Parkinson's model. Cycrimine exhibits antispasmodic activity that can be used in b... | |||
T74988 | DIBA-Cy5 | ||
DIBA-Cy5, a fluorescent DIBA antagonist, consists of DIBA-alkyne and Cyanine5 fluorophores (Cy5) linked by a polyethylene glycol (PEG) chain. It functions as a fluorescent ligand for probe attachment via click chemistry,... | |||
T73272 | VU6019650 | ||
VU6019650 is a potent and selective orthosteric antagonist of M5 mAChR ( IC 50 =36 nM), can be used for opioid use disorder (OUD) relief. VU6019650 can cross blood brain barrier, potentially modulates the mesolimbic dopa... |